We present ToQUBO.jl, a Julia package to reformulate general optimization problems into QUBO instances. This tool aims to convert JuMP problems for straightforward application in physics and physics-inspired solution methods whose normal form is equivalent to QUBO. It automatically maps between source and target models, providing a smooth JuMP modeling experience. We also present a simple interface to connect various annealers and samplers as QUBO solvers bundled in another package, Anneal.jl.